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Cone-beam x-ray phase contrast tomography of biological samples

dc.contributor.authorBartels, Matthias
dc.date.accessioned2013-04-15T07:10:49Z
dc.date.available2014-04-15T07:10:49Z
dc.date.issued2013
dc.identifier.urihttps://doi.org/10.17875/gup2013-92
dc.descriptionSoftcover, 17x24, 205 S.: 44,00 €
dc.format.extentIV, 205
dc.format.mediumPrint
dc.language.isoeng
dc.relation.ispartofseriesGöttingen Series in x-ray Physics
dc.rights.urihttp://creativecommons.org/licenses/by-sa/3.0/
dc.subject.ddc530
dc.titleCone-beam x-ray phase contrast tomography of biological samples
dc.title.alternativeoptimization of contrast, resolution and field of view
dc.typemonograph
dc.price.print44,00
dc.identifier.urnurn:nbn:de:gbv:7-isbn-978-3-86395-134-4-0
dc.identifier.ppn767221664
dc.relation.ppn767221095
dc.description.printSoftcover, 17x24
dc.subject.divisionpeerReviewed
dc.subject.subjectheadingPhysik
dc.relation.isbn-13978-3-86395-134-4
dc.relation.issn2191-9860
dc.identifier.articlenumber8101226
dc.identifier.internisbn-978-3-86395-134-4
dc.identifier.internisbn-978-3-86395-134-4
dc.bibliographicCitation.volume013
dc.type.subtypethesis
dc.subject.bisacSCI055000
dc.notes.oaiprint
dc.subject.vlb640
dc.subject.bicPH
dc.description.abstractengThree-dimensional information of entire objects can be obtained by the remarkable technique of computed tomography (CT). In combination with phase sensitive X-ray imaging high contrast for soft tissue structures can be achieved as opposed to CT based on classical radiography. In this work biological samples ranging from micrometer sized single cells over multi-cellular nerve tissue to entire millimeter sized organs are investigated by use of cone-beam propagationbased X-ray phase contrast. Optimization with respect to contrast, resolution and field of view is achieved by addressing instrumentation, sample preparation and phase reconstruction techniques. By using laboratory sources functional soft tissue within the bony capsule of mouse cochleae is visualized in 3D with unprecedented image quality. At synchrotron storage rings the technique reveals more than 1000 axons running in parallel within a mouse nerve and enables doseefficient three-dimensional cellular imaging as well as two-dimensional imaging at high resolutions below 50 nm.
dc.notes.vlb-printlieferbar
dc.intern.doi10.17875/gup2023-92
dc.identifier.purlhttp://resolver.sub.uni-goettingen.de/purl?isbn-978-3-86395-134-4
dc.identifier.asin3863951344
dc.subject.themaPH


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